POTE1_HUMAN


Gene
Sequence
MSLVPATNYIYTPLNQLKGGTIVNVYGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCLLFSGNYEALPIIYKNGDIVRFHRLKIQVYKKETQGITSSGFASLTFEGTLGAPIIPRTSSKYFNFTTEDHKMVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSMNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEPDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAPFLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDGTGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAEDVI
Molecular Function F:8-hydroxy-2'-deoxyguanosine DNA binding;F:DEAD/H-box RNA helicase binding;F:G-rich single-stranded DNA binding;F:G-rich strand telomeric DNA binding;F:single-stranded telomeric DNA binding;F:telomerase inhibitor activity;F:telomeric D-loop binding;F:telomeric DNA binding;DNA duplex unwinding;establishment of protein localization to telomere;negative regulation of telomerase activity;negative regulation of telomere maintenance via telomerase;positive regulation of DNA helicase activity;positive regulation of DNA strand elongation;positive regulation of helicase activity;positive regulation of telomerase activity;positive regulation of telomere maintenance via telomerase;regulation of DNA helicase activity;regulation of double-strand break repair via nonhomologous end joining;regulation of telomere maintenance via telomerase;telomere assembly;telomere capping;telomere maintenance via telomerase;telomeric D-loop disassembly;
EMBL Protein ID AAW22613.1; BAA91568.1; BAA91988.1; BAB14110.1; BAB15404.1; AAD08852.1; -; EAW83616.1; AAH02923.1; CAB43281.1
UniProt POTE1_HUMAN from Homo sapiens (Human) / Seqs with 100%, 90%, 50% identity / telombin family
iProClass Q9NUX5  (Superfamily:Protection of telomeres protein 1 (hPot1) (POT1-like telomere end- binding protein))
Pfam PF02765  PF16686 
Google Search scholar keyword
PDBj 1XJV 3KJO 3KJP 5H65 5UN7
Info & Models GTOP SWISS-MODEL
CBRC workflows Annotation Comparative Modeling
PCI Q9NUX5
CasaDB POTE1_HUMAN

Database