RPGF1_HUMAN


Gene
Sequence
MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
Molecular Function F:guanyl-nucleotide exchange factor activity;F:Rap guanyl-nucleotide exchange factor activity;F:SH3 domain binding;activation of GTPase activity;activation of MAPKK activity;blood vessel development;cell-cell adhesion;cellular response to cAMP;cellular response to nerve growth factor stimulus;cytokine-mediated signaling pathway;establishment of endothelial barrier;negative regulation of canonical Wnt signaling pathway;negative regulation of ERK1 and ERK2 cascade;negative regulation of neural precursor cell proliferation;negative regulation of protein kinase B signaling;negative regulation of Ras protein signal transduction;nerve growth factor signaling pathway;platelet-derived growth factor receptor signaling pathway;positive regulation of ERK1 and ERK2 cascade;positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;positive regulation of GTPase activity;positive regulation of neuron projection development;positive regulation of Ras protein signal transduction;Rap protein signal transduction;regulation of cell junction assembly;regulation of JNK cascade;signal transduction;transmembrane receptor protein tyrosine kinase signaling pathway;
EMBL Protein ID BAA04770.1; CAH18207.1; -; AAH41710.1
UniProt RPGF1_HUMAN from Homo sapiens (Human) / Seqs with 100%, 90%, 50% identity /
iProClass Q13905
Pfam PF00617  PF00618 
Google Search scholar keyword
PDBj 5L23
Info & Models GTOP SWISS-MODEL
CBRC workflows Annotation Comparative Modeling
PCI Q13905
CasaDB RPGF1_HUMAN

Database