ABL2_HUMAN


Gene
Sequence
MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTETGFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR
Molecular Function F:actin filament binding;F:actin monomer binding;F:ATP binding;F:magnesium ion binding;F:manganese ion binding;F:non-membrane spanning protein tyrosine kinase activity;F:phosphotyrosine residue binding;F:protein kinase activity;F:protein tyrosine kinase activity;cell adhesion;cellular protein modification process;cellular response to retinoic acid;exploration behavior;negative regulation of Rho protein signal transduction;peptidyl-tyrosine phosphorylation;positive regulation of cytosolic calcium ion concentration;positive regulation of neuron projection development;positive regulation of oxidoreductase activity;positive regulation of phospholipase C activity;regulation of actin cytoskeleton reorganization;regulation of apoptotic process;regulation of autophagy;regulation of cell adhesion;regulation of cell motility;regulation of endocytosis;signal transduction;
EMBL Protein ID AAA35553.1; ACK76601.1; ACK76602.1; ACK76603.1; ACK76604.1; -; CAD98092.1; AAY16984.1; EAW91040.1; AAH65912.1
UniProt ABL2_HUMAN from Homo sapiens (Human) / Seqs with 100%, 90%, 50% identity / Tyr protein kinase family
iProClass P42684  (Superfamily:tyrosine-protein kinase, ABL type)
Pfam PF08919  PF07714  PF00017  PF00018 
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Database